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EC number: 931-210-9 | CAS number: 1266534-73-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater invertebrates: EC50(48h) > 100 mg/L (RA FCC catalysts)
Marine water invertebrates: EC50(96 h) > 780 mg/L (RA Zeolite cuboidal)
Key value for chemical safety assessment
Additional information
No data for short-term toxicity to aquatic invertebrates are available for the target substance Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony. Therefore, data from the analogue approach source substance fluidized catalytic cracking (FCC) catalysts were applied to cover the endpoint short-term toxicity to freshwater invertebrates. Data for marine invertebrates were used from the analogue approach source substance Zeolite, cuboidal, crystalline, synthetic, non-fibrous.
The study investigating the effects of FCC catalysts was tested with Daphnia magna according to OECD 202 as limit test. A filtered solution of a nominal test concentration of 100 mg/L was used. Since no immobility of daphnids could be observed in control and filtered test solution, the EC50(48h) was stated as greater than 100 mg/L.
The acute toxicity of Zeolite, cuboidal, crystalline, synthetic, non-fibrous on Penaeus duorarum (a marine shrimp) was determined by Maki and Macek (1978, RL2). The test was conducted according to an US EPA standard guideline (US EPA-660/3-75-009), yielding an EC50 value of > 780 mg/L after 96 h exposure.
Additional data for short-term toxicity to aquatic invertebrates (Daphnia magna) are available for the following source substances which serve as potential data sources for the analogue approach of Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony:
- Source chemical 2 - Zeolite, cuboidal, crystalline, synthetic, non-fibrous:
EC50(24h) = 2808 mg/L, Hooftman and van Drongelen-Sevenhuijsen 1992; EC50(48) > 100 mg/L, Thiébaud H and Chedaille CD, 1996
- Source chemical 5 - Aluminium oxide:
EL50(48h) > 100 mg/L, Tobiensen and Kallquist 1996
In accordance with the target substance, the available data for the source substances also provide a low potential for short-term toxicity to freshwater invertebrates.
The respective references for the source substance data can be found in the data matrix of the justification for the analogue approach, which can be found either in the CSR or as attachment in Iuclid section 13.
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