7-azatridecane-1,13-diamine

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

5 µg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

50 µg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.5 µg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

PNEC marine water (intermittent releases):

5 µg/L

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

1.8 mg/L

Assessment factor:

100

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

186 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

18.6 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

96 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Key information used:

The aquatic toxicity of BHT was determined in reliable short term tests with fish, daphnia, algae and microorganisms. The following key values were obtained:

Fish, Leuciscus idus melanotus: LC50 (48 h): 76 mg/L

Daphnia magna: EC50 (48 h): 9.1 mg/L

Green algae Pseudokirchneriella subcapitata: EC50 (72 h, GR): 5 mg/L, EC10 (72 h, GR): 0.54 mg/L

Activated sludge respiration inhibition: EC50 179 mg/L

Conclusion on classification

Classification according to Regulation (EC) 2008/1272 (CLP)

Classification according Regulation (EC) 2008/1272 (CLP) is performed independently for acute and chronic hazards.

Acute hazard category:

The lowest acute aquatic toxicity of three trophic levels was determined for algae (Pseudokirchneriella subcapitata) with an acute EC50 (72 h, growth rate) of 5 mg/L.

Thus, no acute classification results from the available acute aquatic ecotoxicity data.

 

Chronic hazard category:

Using available acute data, decisive for a possible chronic classification is failure or fulfillment of (1) rapid degradability and / or (2) presence or absence of a bioaccumulation potential.

As substitute for an experimentally determined BCF in fish log KOW is taken as an indicator of bioaccumulation potential. As log KOW (measured value: 1.3), of the submission substance is clearly below the cut-off value according to CLP of 4.0, the submission substance is regarded as non-bioaccumulative.

Rapid biodegradability according to CLP is given for substances, which were assessed as “readily biodegradable” in screening studies (OECD 301), with a minimum of 60% O2-depletion of theoretical maximum within 28 days, and at the same time fulfilling the 10-day-window. This is met by the submission substance. The submission substance is therefore considered as rapidly biodegradable.

No chronic classification results for the submission substance from the available acute data on ecotoxicity, the degradation and bioaccumulation potentials.

Using available chronic data for algae (no other chronic data available for the submission substance), a chronic classification for rapidly degradable substances results

from the EC10 (72 h, growth rate) of 0.54 mg/L. Thus, the final chronic classification according to regulation (EC) 2008/1272 (CLP) is the following:

Category Chronic 3, H 412: Harmful to aquatic life with long lasting effects