Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

All aquatic toxicity tests on fish, invertebrates and aquatic plants as well as on activated sludge showed LC/EC50-values above the water solubility limits of hesperidin (5 mg/l)

Conclusion on classification

Hesperidin is readily biodegradable and has a log POW of less than 0.3. Its acute aquatic toxicity is considered low as its structural analogon diosmin, containing 10 % hesperidin, has been investigated on three different aquatic species (fish, algae and daphnia) at limit concentration of 100 mg/l not showing any effects. As this limit value is more than a factor of 20 above the limit of water solubility of hesperidin (4.93 mg/l) hesperidin is not toxic to aquatic organism.

According to the rules defined within CLP (Regulation (EC) 1272/20008) and DSD (Directive 67/548/EEC) hesperidin is neither to be classified for acute aquatic toxicity nor for chronic aquatic toxicity.