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EC number: 701-016-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No data on acute toxicity to aquatic invertebrates is available for HiMO LAB. Data from LAB (CAS no: 67774-74-7) and HAB (CAS No: 84961-70-6) as structural analogues were used to understand the acute toxicity profile of substance to daphnia. The 48-hr EC50 values were >0.041 mg/L for LAB, and > 1.4 mg/L for HAB. As a consequence, due to the extremely low water solubility, the acute toxicity is above the water solubility (<0.1 mg/L).
Key value for chemical safety assessment
Additional information
Benzene, C16-24 alkyl derivatives are also known as High Molecular Weight Linear Alkylbenzenes (HiMo LAB). The substance is a UVCB. Because of their high molecular weight, they are very similar in composition and properties to the heavy alkylate bottoms (HAB). Based on these structural and functional similarities, data on LAB (CAS no: 67774-74-7) being registered under REACH, LAB Alkylate Bottoms (CAS no: 85117-41-5) described in OECD SIDS dossier, and HAB (CAS no: 84961-70-6) being registered under REACH are suitable as supporting studies in case where specific data on the HiMo LAB is lacking.
To assess the acute toxicity profile of the substance to daphnia, structral analogue approach was used from LAB. Daphnids were exposed to concentrations of 0, 12.5%, 25%, 50%, 75%, and 100% saturated test solution for 48 hrs. At the end of this period, the daphnids were observed for mobility. Though immobilized daphnids were seen at 4 test concentrations, there was no dose-related increase in immobilization, nor was the number of immobilized daphnids significantly increased over negative controls. The 48-hr EC50 is >0.041 mg/L, this is greater than the water solubility for the test substance.
The acute toxicity to daphnia of supporting substance; HAB was determined in OECD 202 guideline study. Groups of 20 daphnids were exposed to concentrations of 0, 0.35, 0.49, 0.70, 0.98, or 1.40 mg/L of test substance. The daphnids were then observed at 24 and 48 hrs after start of exposure for immobilization. At the 24 hr observation, one daphnid at the 0.98 mg/L concentration was immobilized. At the 48-hr observation one daphnid at the 0.70, 0.98, and 1.40 mg/L concentrations was immobilized. The 48-hr EC50 was > 1.4 mg/L test substance, which is greater than the water solubility of the test substance. Concentrations refer to TOC. No effect at saturated solutions (1.4 mg/L).
The EPISUITE QSAR modelling was used to predict the acute toxicity profile of HiMo LAB. Modelled toxicity values for HiMo LAB (C20 and C24 alkyl derv.) confirmed that the aquatic acute toxicity value exceeds (i) the predicted water solubility, indicating the substance is not soluble enough to measure the predicted effect and (ii) the log Kow cutoff value of 5.0 for acute toxicity to daphnia.
According to data from analogue substances and QSAR modelling of HiMo LAB, the substance does not demonstrate acute aquatic toxicity at water soluble concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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