Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
247-557-8
CAS no.:
26264-06-2
Index number:
Molecular formula:
C34H54CaO6S2
SMILES:
[Ca++].CCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O
InChI:
InChI=1S/2C17H28O3S.Ca/c2*1-2-3-4-5-6-7-8-9-10-13-16-14-11-12-15-17(16)21(18,19)20;/h2*11-12,14-15H,2-10,13H2,1H3,(H,18,19,20);/q;;+2/p-2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
9
Of which contain:
10 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed, causes serious eye damage, may cause long lasting harmful effects to aquatic life and causes skin irritation.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is toxic to aquatic life with long lasting effects.

Breakdown of all 2012 C&L notifications submitted to ECHA

Skin Irrit. 2 H315
Eye Dam. 1 H318
Aquatic Chronic 4 H413
Acute Tox. 4 H302
Aquatic Chronic 3 H412
Aquatic Chronic 2 H411
Acute Tox. 4 H312
Acute Tox. 4 H332
Eye Irrit. 2 H319
Not Classified
Acute Tox. 2 H310
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 8 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases and plant protection products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of chemicals at dedicated facilities, laboratory work and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture) and metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: lubricants and greases, washing & cleaning products, hydraulic fluids and metal working fluids.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: and chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, treatment of articles by dipping and pouring, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use as processing aid and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following products: lubricants and greases, plant protection products and washing & cleaning products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: lubricants and greases, metal working fluids and hydraulic fluids.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: and chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, closed processes with no likelihood of exposure and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

General statements

If medical advice is needed, have product container or label at hand. Keep out of reach of children.

Prevention statements

When handling this substance: wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Advanced Material, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Canada Co.\Cie, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • KAJO GmbH, Boschstr. 13 59609 Anröchte Nordrhein-Westfalen Germany
  • REACH 2008 Ltd, J.K.Mladost-1, bl.32, entr.A, fl.5, ap.10 J.K.Mladost-1, bl.32, entr.A, fl.5, ap.10 1784 Sofia Bulgaria Bulgaria
  • [Confidential], [Confidential]

Substance names and other identifiers

1371A
Other
Benzenesulfonic acid, dodecyl-, calcium salt
Other
Benzenesulfonic acid, dodecyl-, calcium salt (2:1)
Other
Calcium alkylaromatic sulfonate
Other
Calcium alkylbenzenesulfonate
Other
Calcium bis(dodecylbenzenesulfonate)
Other
Calcium dodecylbenzenesulfonate
Other
Calcium dodecylbenzenesulphonate
EC Inventory, REACH pre-registration
Calcium dodecylbenzenesulphonate
REACH pre-registration, Other
Calcium dodecylbenzensulfonate
Other
Calcium N-dodecylbenzenesulfonate
Other
Casul 70HF
Other
Dodecylbenzenesulfonic acid calcium salt
Other
Dodecylbenzensulfonic acid calcium salt
Other
Sinnozon NCX 70
Other
Soprofor S 70
Other
Wettol EM 1
Other
1-propanol, 2-methyl-
C&L Inventory
Benzenesulfonic acid, dodecyl-, calcium salt
C&L Inventory
C12 Alkylbenzenesulphonate, calcium salt
C&L Inventory
Calcium 4-dodecan-3-ylbenzenesulfonate
C&L Inventory
Calcium bis(2-dodecylbenzenesulfonate)
C&L Inventory, Registration dossier
Calcium dodecylbenzene sulfonate
C&L Inventory
calcium dodecylbenzene sulphonate
C&L Inventory
Calcium dodecylbenzenesulfonate
C&L Inventory
CALCIUM DODECYLBENZENESULPHONATE
C&L Inventory, Registration dossier
calcium dodecylbenzenesulphonate
C&L Inventory, Registration dossier
calcium dodecylbenzenesuphonate
C&L Inventory
calciumdodecylbenzenesulfonate
C&L Inventory
Abeson Ca
C&L Inventory
CaDDBS
Registration dossier
Calcium alkylaromatic sulfonate
Registration dossier
Calcium alkylbenzene sulfonate
Registration dossier
Calcium dodecylbenzene sulphonate
Registration dossier
Calcium linear C12 Alkylbenzene sulfonate
Registration dossier
Calcium N-dodecylbenzenesulfonate
Registration dossier
Dodecylbenzene Sulfonic Acid Calcium CaDDBS
Registration dossier
Dodecylbenzenesulfonic acid, calcium salt;
Registration dossier
TH 35
Registration dossier
105864-16-2
CAS number
Other
12068-14-3
CAS number
Other
1219441-08-3
CAS number
Other
26264-06-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
29062-23-5
CAS number
Other
372965-63-4
CAS number
Other
41934-13-8
CAS number
Other
705264-21-7
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Compact (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
349.84 °C @ 0 Pa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
349.84 °C

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
843.05 °C @ 0 Pa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
843.05 °C

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
1.04 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.04

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 3 studies processed
R Log Pow
1.96 - 4.77 @ 25 °C and pH 7 [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
4.77 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
852.7 µg/L @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
852.7 µg/L @ 25 °C

Solubility in organic solvents / fat solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
30 mN/m @ 120 mg/L

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
149 °C @ 101.5 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
149 °C

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
0.7 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
0.7

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
960 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
960 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 1 study processed
R Degradation rate constant (OH radicals)
0 cm³ molecule-1 d-1 [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
7.92 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life for hydrolysis
1 years @ 50 °C

Phototransformation in water

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in water
2 h

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 5 studies submitted
  • 4 studies processed
C Interpretation of results
Readily biodegradable (100%) [4]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in soil
23.1 days @ 20 °C

Bioaccumulation: aquatic / sediment

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 3 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
70.79 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
70.79 L/kg ww

Adsorption/desorption

Study results
  • 5 studies submitted
  • 5 studies processed
R Koc
2 360 - 9 076 L/kg @ 20 °C and 26 % organic carbon [5]
R log Koc
3.21 - 3.886 L/kg @ 20 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
7 699

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 25 °C and 101.325 kPa [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 0.136 % [1]
R Water 12 % [1]
R Soil 87.5 % [1]
R Sediment 0.326 % [1]
R Suspended sediment 0 % [1]
R Biota 0 % [1]
R Aerosol 0 % [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 280 µg/L (1)
Intermittent releases (freshwater) 654 µg/L (1)
Marine water 458 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 50 mg/L (1)
Sediment (freshwater) 27.5 mg/kg sediment dw (1)
Sediment (marine water) 2.75 mg/kg sediment dw (1)
Hazard for Air
Air 10 mg/m³ (1)
Hazard for Terrestrial Organism
Soil 25 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 20 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 17 studies submitted
  • 12 studies processed
P/RResults
LC50 (4 days) 1.74 - 7.16 mg/L [9]
LC50 (48 h) 2.8 - 6 mg/L [6]
LC50 (24 h) 4.5 - 6.4 mg/L [2]
LC0 (4 days) 4 mg/L [2]
LC100 (4 days) 4.3 mg/L [2]

Type of Study provided
Studies with data
Key study 3 1
Supporting study 5
Weight of evidence 4 4
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 11 studies submitted
  • 9 studies processed
P/RResults
NOEC (6.533 months) 630 µg/L [2]
NOEC (3 months) 250 µg/L [2]
NOEC (30 days) 230 µg/L [1]
NOEC (28 days) 1 - 3.2 mg/L [4]
LOEC (6.533 months) 1.2 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence 4 4
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 15 studies submitted
  • 9 studies processed
P/RResults
EC50 (48 h) 2.5 mg/L [2]
EC50 (24 h) 12 mg/L [2]
LC50 (48 h) 1.276 - 5.12 mg/L [5]
LC50 (3 h) 40 mg/L [2]
EC0 (24 h) 6 mg/L [2]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 6
Weight of evidence 3 3
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 10 studies submitted
  • 9 studies processed
P/RResults
NOEC (30 days) 253 µg/L [1]
NOEC (28 days) 2 - 4 mg/L [4]
NOEC (21 days) 1.18 - 3.25 mg/L [8]
LOEC (28 days) 4 mg/L [2]
LOEC (21 days) 2.25 - 3.75 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 4 4
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 5 studies processed
P/RResults
EC50 (4 days) 2.736 - 29 mg/L [3]
EC50 (72 h) 21 - 65.4 mg/L [4]
NOEC (30 days) 1.266 mg/L [1]
NOEC (72 h) 7.9 mg/L [2]
LOEC (72 h) 15.1 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
65.4 mg/L
EC50 for marine water algae
6.54 mg/L
EC10 or NOEC for freshwater algae
7.9 mg/L
EC10 or NOEC for marine water algae
790 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (7 days) 2.7 mg/L [2]
NOEC (7 days) 900 µg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
2.7 mg/L
EC50 for marine water plants
270 µg/L
EC10 or NOEC for freshwater plants
900 µg/L
EC10 or NOEC for marine water plants
90 µg/L

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 h) 500 - 723 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
500 mg/L
EC10 or NOEC for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
NOEC (28 days) 81 mg/kg sediment dw [2]
NOEC (72 h) 200 mg/kg sediment dw [2]
EC10 (72 h) 275 mg/kg sediment dw [2]
EC50 (28 days) 105 mg/kg sediment dw [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater sediment
105 mg/kg sediment dw
EC50 / LC50 for marine water sediment
10.5 mg/kg sediment dw
EC10 / LC10 or NOEC for freshwater sediment
275 mg/kg sediment dw
EC10 / LC10 or NOEC for marine water sediment
27.5 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
NOEC (14 days) 250 - 667 mg/kg soil dw [4]
LC50 (14 days) 1 - 1.333 g/kg soil dw [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg soil dw
Long-term EC10 / LC10 / NOEC
250 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
EC10 (21 days) 85 - 147 mg/kg soil dw [12]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
425 mg/kg soil dw
Long-term EC10 / LC10 / NOEC
85 mg/kg soil dw

Toxicity to terrestrial plants

Study results
  • 7 studies submitted
  • 5 studies processed
P/RResults
NOEC (5 months) 10 mg/kg soil dw [2]
NOEC (30 days) 1.266 mg/kg soil dw [1]
EC10 (14 days) 80 - 200 mg/kg soil dw [6]
EC50 (5 months) 100 mg/kg soil dw [2]
EC50 (14 days) 300 - 1 641 mg/kg soil dw [6]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
100 mg/kg soil dw
Long-term EC10 / LC10 / NOEC
10 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOEC (45 days) 200 mg/kg diet [2]
NOEL (45 days) 25 mg/kg bw/day [2]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg food
Long-term EC10 / LC10 / NOEC
200 mg/kg food

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 52 mg/m³ acute toxicity
Acute /short term: (DNEL) 52 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 52 mg/m³ acute toxicity
Acute /short term: (DNEL) 52 mg/m³ acute toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 57.2 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 80 mg/kg bw/day acute toxicity
Local Effects
Long-term: (DNEL) 1.57 mg/cm² acute toxicity
Acute /short term: (DNEL) 1.57 mg/cm² acute toxicity
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 26 mg/m³ acute toxicity
Acute /short term: (DNEL) 26 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 26 mg/m³ acute toxicity
Acute /short term: (DNEL) 26 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 28.6 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 40 mg/kg bw/day acute toxicity
Local Effects
Long-term: (DNEL) 787 µg/cm² acute toxicity
Acute /short term: (DNEL) 787 µg/cm² acute toxicity
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 13 mg/kg bw/day acute toxicity
Acute /short term: (DNEL) 13 mg/kg bw/day acute toxicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 3 3
Other
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study 2
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Dermal: 0.3 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 5 studies processed
P/RResults
LD50 775 - 1 300 mg/kg bw (rat) [5]
M/CInterpretations of results
Category 4 based on GHS criteria [5]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence 2 2
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 310 mg/m³ air (rat) [2]
M/CInterpretations of results
Other [2]

inhalation
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 4 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
LD50 212 - 2 000 mg/kg bw (rabbit) [4]
M/CInterpretations of results
Other [4]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
other routes
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 1 300 mg/kg bw
Inhalation route:
No adverse effect observed LC50 310 mg/m³ air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence 3 3
Other
Data waiving
no waivers
Study data: eye
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2 1
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 11 studies submitted
  • 10 studies processed
P/RResults
NOAEL (rat): 50 - 250 mg/kg bw/day [10]
NOAEL (monkey): 150 mg/kg bw/day [2]
LOAEL (rat): 200 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence 4 5
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: dermal
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 286 mg/kg bw/day [2]
LOAEL (rat): 286 mg/kg bw/day [2]

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence 1 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 100 mg/kg bw/day (subacute, rat)
Dermal route - systemic effects:
No adverse effect observed NOAEL 286 mg/kg bw/day (subacute, rat)
Dermal route - local effects:
No adverse effect observed NOAEL 1.6 mg/cm² (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 4.35 mg/m³ (subacute, rat)
Inhalation route - local effects:
No adverse effect observed NOAEC 4.35 mg/m³ (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1
Supporting study 1
Weight of evidence 2 2
Other
Data waiving
no waivers
Study data: in vivo
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study 3
Weight of evidence 1 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 250 mg/kg bw/day (chronic, rat)
Dermal route:
No adverse effect observed NOAEL 6.25 mg/kg bw/day (chronic, rat)
Inhalation route:
No adverse effect observed NOAEC 10.87 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study
Weight of evidence 3 3
Other
Data waiving
no waivers
Study data: developmental
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 4
Weight of evidence 3 3
Other
Data waiving
no waivers
Study data: other studies
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 400 mg/kg bw/day (subacute, rat)
Dermal route:
No adverse effect observed NOAEL 10 mg/kg bw/day (subacute, rat)
Inhalation route:
No adverse effect observed NOAEC 17.4 mg/m³ (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 400 mg/kg bw/day (subacute, rat)
Dermal route:
No adverse effect observed NOAEL 20 mg/kg bw/day (subacute, rat)
Inhalation route:
No adverse effect observed NOAEC 17.4 mg/m³ (subacute, rat)

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant