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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

The 21 day NOEC of C11.8 LAS to Daphnia magna was 1.18 mg/L, based on survival and reproduction.  The 21 day LC50 was 1.67 mg/L. Results are based on the mean measured concentration of the active ingredient. The data here are for a C11.8 LAS and when normalized to a C11.6 LAS, the value is 1.41 mg/L (method: van de Plassche et al., 1999).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.41 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
1.41 mg/L

Additional information

The long-term toxicity of 11.8 LAS was evaluated in a 21 day survival and reproduction test with Daphnia magna, following the OECD 211 guideline. Four replicates per concentration, 5 organisms per replicate, were tested in a flow-through system (a modified Mount and Brungs proportional diluter). Mean measured concentrations were: Control, 0.32, 0.59, 1.18, 2.52, and 4.85 mg/L C11.8LAS (active ingredient).

Survival was monitored at 24 hr, 96 hr, 7 days and daily thereafter. Reproduction was monitored beginning with the production of the first brood on day 7 or 8, and daily thereafter. LC50s and EC50s were calculated by probit analysis. Results are based on the mean measured concentration of the active ingredient.

The 21-day NOEC was 1.18 mg/L, based on both survival and reproduction. The 21-day LC50 was 1.67 mg/L (95% CL 1.28 -2.18 mg/L). The 21 -day EC50s, based on total young production, average brood size, and % days reproduction occurred, were 1.50, 2.30, and 2.31 mg/L, respectively. The data here are for a C11.8 LAS and when normalized to a C11.6 LAS, the value is 1.41 mg/L (method: van de Plassche et al., 1999).

Based on the data for linear and branched alkylbenzene sulfonates, linear structures are more toxic than branched structures. Therefore, data on linear materials, e.g., the chronic aquatic studies using LAS, are considered to be a worst case scenario.