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EC number: 500-086-4 | CAS number: 35238-34-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to O.E.C.D. Test Guideline No. 209 with GLP compliance.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 8192 (Water quality - Test for inhibition of oxygen consumption by activated sludge for carbonaceous and ammonium oxidation)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-Acetone, polymer with phenol
- EC Number:
- 500-086-4
- EC Name:
- 2-Acetone, polymer with phenol
- Cas Number:
- 35238-34-7
- Molecular formula:
- (C6H6O.C3H6O)x
- IUPAC Name:
- 2-Propanone, polymer with phenol
- Reference substance name:
- 2-Acetone polymer with phenol
- IUPAC Name:
- 2-Acetone polymer with phenol
- Reference substance name:
- : 2-Propanone, polymer with phenol
- IUPAC Name:
- : 2-Propanone, polymer with phenol
- Reference substance name:
- BPA-Tars
- IUPAC Name:
- BPA-Tars
- Details on test material:
- As per IUCLID5 Sections 1.1. -1.4.
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Details on test solutions:
- Direct weightings of the test substance were made to achieve the final concentrations of: 1000, 1800, 3200,5600 and 10000 mg/L.
Test organisms
- Test organisms (species):
- activated sludge of a predominantly industrial sewage
- Details on inoculum:
- Sludge from a laboratory scale sewage treatment plant was settled and the supernatant was decanted. After centrifuging (20 min at 4000 rpm and 20°C) the supernatant was decanted. Then approximately 1 g of the wet sludge was dried in order to calculate the amount of sludge to achieve a concentration of activated sludge of 6 g/L (dry weight) suspended solids. The dry sludge was resuspended in a defined synthetic medium for exposure.
- the calculated amount of sludge was first dissolved in synthetic medium and than filled up to a defined end volume with deionised water
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Remarks on exposure duration:
- with aeration
- Post exposure observation period:
- None.
Test conditions
- Hardness:
- No data
- Test temperature:
- 20 ± 2°C
- pH:
- 7 ± 0.2
- Dissolved oxygen:
- Permanent aeration
- Salinity:
- No data
- Nominal and measured concentrations:
- 1.0, 1.8, 3.2, 5.6 and 10 gm/L nominal
- Details on test conditions:
- Exposure was conducted in 300 mL Erlenmeyer flasks with 6.0 gm/L dry weight activated sludge and aeration. Following three hours of contact the contents of the Erlenemeyer flasks were transfered to BOD bottles and the oxygen content measured with O2-meter redox electrode. .
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 4 593 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Details on results:
- The inhibition of sludge respiration by BPA-Tars was dose-dependent and reached 87% inhibition relative to the control at the high nominal dose level of 10 gm/L. The positive control 3,5-dichlorophenol caused a 75% inhibition of sludge respiration.
- Results with reference substance (positive control):
- 3,5-Dichlorophenol induced a 75% reduction in the sludge respiration rate at 20 mg/L.
- Reported statistics and error estimates:
- No data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The estimated EC50 value of 4.54 gm/L for 2-Acetone polymer with phenol (BPA-Tars) suggests that BPA-Tars has little or no potential to inhibit the respiration of activated sludge. Therefore, BPA-Tars will be effectively removed by STPs.
- Executive summary:
2 -Acetone polymer with phenol (BPA-Tars) was assessed for the ability to inhibit the biological activity of activated sewage sludge by an O.E.C.D. Test Guideline No. 209 study conducted with GLP compliance. The estimated EC50 value of 4.54 gm/L for BPA-Tars suggests that BPA-Tars has little or no potential to inhibit the respiration of activated sludge. Therefore, BPA-Tars will be effectively removed by STPs and not inhibit the removal of other waste streams.
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