Registration Dossier

Classification & Labelling & PBT assessment

PBT assessment

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PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

8.1.2. PBT/vPvB criteria and justification

Persistence (P) Assessment:

A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation)

Several ready biodegradability studies are available demonstrating octane to be readily biodegradable. This is best demonstrated by Haines and Alexander (1974), who showed biodegradation of octane up to 70% after 10 days.

Therefore, the substance does not meet the Persistent (P) or very Persistent (vP) criteria.

Bioaccumulation (B) Assessment:

An evaluation of representative hydrocarbon structures indicates no structures meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria. A BCF was measured to be 199 (Donkin et al. 1989). Based on the screening criteria for bioaccumulation stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008), octane is considered unlikely to be bioaccumulative.

Toxicity (T) Assessment:

Environmental Toxicity:
No representative structures were identified as PBT or vPvB, therefore a toxicity assessment is not needed. None of the measured or calculated data for octane is within the criteria for toxicity stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008). Therefore this substance is not considered toxic (T).

 

Human Health Hazards Assessment (T)

Carcinogenicity:

The available data on octane do notwarrant classification for carcinogenicity under Dir 67/548/EEC or GHS/CLP.

Mutagenicity:

The available data indicate that octane is not genotoxic or mutagenic and do not warrant classification for carcinogenicity under Dir 67/548/EEC or GHS/CLP.

Reproductive Toxicity:

 

There is no evidence that octane causes reproductive or developmental toxicity. The available data indicate that members of the C7-C9 aliphatic hydrocarbon solvent category are not toxic to reproduction and do not warrant classification under Dir 67/548/EEC or GHS/CLP.