Registration Dossier
Registration Dossier
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EC number: 203-892-1 | CAS number: 111-65-9
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
8.1.2. PBT/vPvB criteria and justification
Persistence (P) Assessment:
A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation)
Several ready biodegradability studies are available demonstrating octane to be readily biodegradable. This is best demonstrated by Haines and Alexander (1974), who showed biodegradation of octane up to 70% after 10 days.
Therefore, the substance does not meet the Persistent (P) or very Persistent (vP) criteria.
Bioaccumulation (B) Assessment:
An evaluation of representative hydrocarbon structures indicates no structures meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria. A BCF was measured to be 199 (Donkin et al. 1989). Based on the screening criteria for bioaccumulation stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008), octane is considered unlikely to be bioaccumulative.
Toxicity (T) Assessment:
Environmental Toxicity:
No representative structures were identified as PBT or vPvB, therefore a toxicity assessment is not needed. None of the measured or calculated data for octane is within the criteria for toxicity stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008). Therefore this substance is not considered toxic (T).
Human Health Hazards Assessment (T)
Carcinogenicity:
The available data on octane does not warrant classification for carcinogenicity under GHS/CLP.
Mutagenicity:
The available data indicate that octane is not genotoxic or mutagenic and do not warrant classification for carcinogenicity under GHS/CLP.
Reproductive Toxicity:
There is no evidence that octane causes reproductive or developmental toxicity. The available data indicate that octane is not toxic to reproduction and does not warrant classification under GHS/CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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