Registration Dossier
Registration Dossier
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EC number: 500-036-1 | CAS number: 25214-70-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The Yokohoma Laboratories study was carried out to the highest quality standards and delivered the lowest LC50 for fish..
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 20.6 mg/L
Additional information
A full discussion on the justification on read-across of data for the 4,4´-isomer of MDA for oligomeric MDA in the scope of REACH is presented in section 7.6 of this CSR.
The Yokohoma Laboratories study is highly detailed and was given a reliability of one because of compliance with GLP and inclusion of certificate. The 96h LC50 value of 20.6mg/l indicates that 4,4'-MDA has some toxicity to fish, though results elsewhere confirm that for 4,4'-MDA fish are not the most sensitive species of the three trophic levels of the base-set (fish, daphnia and algae).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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