Registration Dossier
Registration Dossier
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EC number: 425-660-0 | CAS number: 165101-57-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- other: Summary of notification dossier of a new chemical substance in accordance with directive 92/32/EEC (Article 7/8/9/12) O.J.L. 154, Volume 35, 5 June 1992
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- not specified
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 4.2
- Temp.:
- 25 °C
- Remarks on result:
- other: pH value not reported.
- Details on results:
- The material is known to be unstable in water systems under neutral or acidic conditions, so the mobile phase was buffered to pH 8.
Three main peaks were observed from the test substance indicating that some degradation had occurred. Since the reaction in water results in the formation of two substances with reasonable water solubility, it is assumed that the peak with the longest retention time (and also with the largest area) is that of the test substance. - Conclusions:
- Using the HPLC method the partition coefficient (log Pow) of Incozol 2 was determined to be ca. 4.2 at 25 °C .
- Executive summary:
The partition coefficient of Incozol 2 was determined according to EU method A.8 (HPLC method). The partition coefficient (log Pow) of Incozol 2 was determined to be ca. 4.2 at 25 °C.
Reference
Description of key information
Using the HPLC method the partition coefficient (log Pow) of Incozol 2 was determined to be ca. 4.2 at 25 °C .
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.2
- at the temperature of:
- 25 °C
Additional information
The partition coefficient of Incozol 2 was determined according to EU method A.8 (HPLC method). The partition coefficient (log Pow) of Incozol 2 was determined to be ca. 4.2 at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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