Registration Dossier
Registration Dossier
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EC number: 424-090-1 | CAS number: 10097-02-6 DMBA
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- other: SNIF Report
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: 87/302/EWG, S.118
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
- Test type:
- other: aerobic
- Total exposure duration:
- 3 h
- Key result
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 320 mg/L
- Key result
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- 699 mg/L
- Executive summary:
The testing of activated sludge in respiration inhibition test according to OECD 209 guideline under GLP condition show inhibition after 3h of exposure as IC 50= 699 mg/L. The no observed effect concentration after 3 h of exposure was established as NOEC = 320 mg/L.
Reference
Description of key information
Activated Sludge, Respiration Inhibition Test test was performed according toOECD Guideline 209. Inhibitory effects on the respiration of activated sewage sludge after 3 hours of exposure at the test concertation of 100mg/L was not observed. The no observed effect concertation was established as NOEC = 100 mg/L and the IC 50 was established as more than 100 mg/L. The test was performed according to OECD 209 guideline under GLP condition.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
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