Registration Dossier
Registration Dossier
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EC number: 406-760-3 | CAS number: 42221-52-3 2,3,4,5-TETRACHLORBENZOYLCHLORID
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: Becam-assay
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 1 991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: directive 84/449/EEC, B.5 point 1.6.1
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,3,4,5-tetrachlorobenzoylchloride
- EC Number:
- 406-760-3
- EC Name:
- 2,3,4,5-tetrachlorobenzoylchloride
- Cas Number:
- 42221-52-3
- Molecular formula:
- C7HCl5O
- IUPAC Name:
- 2,3,4,5-tetrachlorobenzoyl chloride
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals / tissue source
- Species:
- other: bovine eyes(BE)
Test system
- Amount / concentration applied:
- 0.060000ml
- Number of animals or in vitro replicates:
- 5
Results and discussion
In vivo
Results
- Irritation parameter:
- other: means scores
- Score:
- 2.5
- Remarks on result:
- other: moderate
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information
- Conclusions:
- with reference of directive 84/449/EEC, B.5 point 1.6.1 the Becam-assay was choosen for the determination of the eye irritation potential.
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