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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline and GLP compliant study report.
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
yes
Remarks:
log Pow was estimated based on solubility data in octanol and water
Principles of method if other than guideline:
Estimation of log Pow of test item using the solubility of test item in n-octanol and water
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
not specified
Type:
log Pow
Partition coefficient:
< -2.7
Temp.:
20 °C
Remarks on result:
other: calculated result
Conclusions:
As the results of the preliminary test indicated that the log Pow of the test item based on the solubility in pure solvents was < -2, the test was considered completed with: log Pow < -2.7

Description of key information

As the results of the preliminary test indicated that the log Pow of the test item based on the solubility in pure solvents was < -2, the test was considered completed with: log Pow < -2.7

Key value for chemical safety assessment

Additional information