Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: accepted calculation method

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Guideline:
other: EPIWIN calculation
Principles of method if other than guideline:
Calculation with EPIWIN (4.10) ; KOWIN version. 1.68
GLP compliance:
no
Type of method:
other: calculation
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenylephrine hydrochloride
EC Number:
200-517-3
EC Name:
Phenylephrine hydrochloride
Cas Number:
61-76-7
Molecular formula:
C9H13NO2.ClH
IUPAC Name:
phenylephrine hydrochloride

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-3.1
Temp.:
25 °C

Applicant's summary and conclusion