Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bio-degradation in water by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium 3-methylsulphanilate
EC Number:
264-172-0
EC Name:
Sodium 3-methylsulphanilate
Cas Number:
63450-43-1
Molecular formula:
C7H9NO3S.Na
IUPAC Name:
sodium 3-methylsulphanilate
Details on test material:
- Name of test material: sodium 3-methylsulphanilate
- Substance type:organic
- Physical state:solid

Study design

Oxygen conditions:
other: estimated
Duration of test (contact time):
38 d
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
test mat. analysis
Reference substance
Reference substance:
not specified

Results and discussion

% Degradation
Parameter:
other: Halflife
Value:
50
Sampling time:
38 d
Remarks on result:
other: Other details not available
Details on results:
Half life = 38 days

Any other information on results incl. tables

Media

Half life

(days)

Percent in Medium

Water

38

35%

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable
Conclusions:
The half life period of sodium 3-methylsulphanilate in water is 38 days and based on this value it can be concluded that the chemical is not persistent in water medium since the half life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage of sodium 3-methylsulphanilate in water medium is 35%. This coupled with the dilution of water shall result in ready biodegradabililty of the chemical.
Executive summary:

The half life period of sodium 3-methylsulphanilate in water is 38 days and based on this value it can be concluded that the chemical is not persistent in water medium since the half life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage of sodium 3-methylsulphanilate in water medium is 35%. This coupled with the dilution of water shall result in ready biodegradabililty of the chemical.