Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-308-1 | CAS number: 1335203-19-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Findings from a chronic sediment OECD 225 study showed that the registered substance did not cause any long-term effects on reproduction and growth (biomass) in the benthic sediment blackworm, Lumbriculus variegatus, after 28 days of exposure in sediment at 0, 11, 33 and 101 mg/kg. The 28-day NOEC was ≥ 101 mg/kg soil d.w. based on no observed adverse effects on reproduction and growth. Hence, the registered substance showed no long-term toxicity or adverse effects to organisms in sediment. No PNEC for sediment could be derived for quantitative risk assessment. However, it is possible to qualitatively conclude that the registered substance does not pose an unacceptable risk to freshwater sediment-dwelling organisms
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 101 mg/kg sediment dw
Additional information
After 28 days of exposure, there were no statistically significant treatment-related effects on the reproductive output (number of live worms) or growth (e.g., biomass - dry weight) when the treatment groups (11, 33 and 101 mg/kg nominal) were compared to the control group (p= 0.05, Dunnett’s test). As such, the 28-day NOEC for both reproduction and growth is equal to or greater than the highest loading concentration tested (101 mg/kg). The 28-day EC10 value (reproduction and growth) is expected or can be deduced to be greater than 101 mg/kg since no differences were observed between the control and treated groups.
Overall, the findings from this chronic OECD 225 toxicity test indicate that the registered substance did not cause any long term effect on mortality, reproduction or growth in the benthicLumbriculus variegatusafter 28 days of exposure in sediment. In addition, no behavioral effects were observed in the blackworms when the treatment groups were compared with the control group. No mortality was observed at study termination.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.