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Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29 June 2010 - 03 August 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study has been performed according to OECD and EC guidelines and according to GLP principles.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part III: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 3, Class 4, Division 5.1 and Class 9, Test N.4 , 2003
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part III: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 3, Class 4, Division 5.1 and Class 9, Test N1, 2003.
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Lysine hydrochloride
EC Number:
211-519-9
EC Name:
Lysine hydrochloride
Cas Number:
657-27-2
Molecular formula:
C6H14N2O2.ClH
IUPAC Name:
lysine hydrochloride
Details on test material:
- Name of test material (as cited in study report): L-Lysine Monohydrochloride
- Molecular formula: C6H14N2O2HCl
- Molecular weight: 182.65
- Substance type: Beige powder with lumps
- Physical state: Solid
- Analytical purity: 99.72%
- Impurities (identity and concentrations): -
- Composition of test material, percentage of components: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No.: 0148
- Expiration date of the lot/batch: 28 May 2012
- Stability under test conditions: Stable
- Storage condition of test material: At room temperature in the dark
- Other: -

Results and discussion

Relative self-ignition temperature (solids)
Key result
Remarks on result:
no self ignition observed under the test conditions

Any other information on results incl. tables

No exothermic effect of the test substance was observed. It demonstrated that the test substance is “not a self-heating substance”. According to the guideline, no further testing was required.

 

After the experiment, the test substance appeared to have been unchanged.

Applicant's summary and conclusion

Conclusions:
The self-heating temperature of L-Lysine Monohydrochloride was determined by Test 1 of the Modified Bowes-Cameron Cage test.

Based on the results obtained, the test substance is considered “not a self-heating substance”.

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