Registration Dossier
Registration Dossier
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EC number: 606-191-2 | CAS number: 18979-61-8
Endpoint summary
Administrative data
Description of key information
An oral LD50 study for 4-n-butylresorcinol is reported in a scientific journal publication which investigates the toxicty of a number of 4-n-alkylresorcinols. Approx. 50% of the animals (rat) died at the lowest test level (circa 500 mg/kg bw). Approx. 80% of animals died at the highest dose level (circa 1000 mg/kg bw).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 500 mg/kg bw
Additional information
The LD50 value for 4-n-butylresorcinol is sourced from a scientific journal publication which also reports on acute toxicity test results for 4-n-hexylresorcinol. Information on 4-n-hexylresorcinol is available from a WHO review, which cites and supports the findings from this scientic journal publication. Therefore the study is considered as reliable with restrictions and an LD50 of 500 mg/kg bw (rat) appears appropriate.
Justification for classification or non-classification
LD50 (rat) = 500 mg/kg bw
In accordance with Directive 67/548 the substance should be classified as R22: Harmful if swallowed
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