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Description of key information

An oral LD50 study for 4-n-butylresorcinol is reported in a scientific journal publication which investigates the toxicty of a number of 4-n-alkylresorcinols. Approx. 50% of the animals (rat) died at the lowest test level (circa 500 mg/kg bw). Approx. 80% of animals died at the highest dose level (circa 1000 mg/kg bw).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
500 mg/kg bw

Additional information

The LD50 value for 4-n-butylresorcinol is sourced from a scientific journal publication which also reports on acute toxicity test results for 4-n-hexylresorcinol. Information on 4-n-hexylresorcinol is available from a WHO review, which cites and supports the findings from this scientic journal publication. Therefore the study is considered as reliable with restrictions and an LD50 of 500 mg/kg bw (rat) appears appropriate.

Justification for classification or non-classification

LD50 (rat) = 500 mg/kg bw

In accordance with Directive 67/548 the substance should be classified as R22: Harmful if swallowed