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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

An oral LD50 study for 4-n-butylresorcinol is reported in a scientific journal publication which investigates the toxicty of a number of 4-n-alkylresorcinols. Approx. 50% of the animals (rat) died at the lowest test level (circa 500 mg/kg bw). Approx. 80% of animals died at the highest dose level (circa 1000 mg/kg bw).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
500 mg/kg bw

Additional information

The LD50 value for 4-n-butylresorcinol is sourced from a scientific journal publication which also reports on acute toxicity test results for 4-n-hexylresorcinol. Information on 4-n-hexylresorcinol is available from a WHO review, which cites and supports the findings from this scientic journal publication. Therefore the study is considered as reliable with restrictions and an LD50 of 500 mg/kg bw (rat) appears appropriate.

Justification for classification or non-classification

LD50 (rat) = 500 mg/kg bw

In accordance with Directive 67/548 the substance should be classified as R22: Harmful if swallowed