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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25.10.2012 to 06.11.2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Measurement of capacity of a compound to dissociate into respective ions.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,2-trifluoroacetamide
EC Number:
206-559-9
EC Name:
2,2,2-trifluoroacetamide
Cas Number:
354-38-1
Molecular formula:
C2H2F3NO
IUPAC Name:
2,2,2-trifluoroacetamide
Test material form:
solid: crystalline
Details on test material:
- Name of test material : 2,2,2-trifluoroacetamide
- Molecular formula : C2H2F3NO
- Substance type: Organic
- Physical state: Solid

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
0
Temp.:
23 °C
No.:
#2
pKa:
0
Temp.:
23 °C
No.:
#3
pKa:
0
Temp.:
23 °C

Applicant's summary and conclusion

Conclusions:
The average experimental pKa value for 2,2,2-trifluoroacetamide was found to be 0.000000004 at 23 deg C indicating that it has dissociating properties.
Executive summary:

The average experimental pKa value for 2,2,2-trifluoroacetamide was found to be 0.000000004 at 23 deg C indicating that it has dissociating properties.