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EC number: 206-559-9 | CAS number: 354-38-1
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25.10.2012 to 06.11.2012
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 2,2,2-trifluoroacetamide
- EC Number:
- 206-559-9
- EC Name:
- 2,2,2-trifluoroacetamide
- Cas Number:
- 354-38-1
- Molecular formula:
- C2H2F3NO
- IUPAC Name:
- 2,2,2-trifluoroacetamide
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material : 2,2,2-trifluoroacetamide
- Molecular formula : C2H2F3NO
- Substance type: Organic
- Physical state: Solid
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 0.725
- Temp.:
- 23 °C
- pH:
- 4.83
- Details on results:
- Converting the above Pow value into its Log value, the Log Pow of 2,2,2-trifluoroacetamide is 0.72509 at temperature 23 degC and pH of 4.83
Applicant's summary and conclusion
- Conclusions:
- The experimental value of octanol water partition co-efficient (log Pow) of 2,2,2-trifluoroacetamide by Shake flask method was found to be 0.72509 at temperature 23 degC and pH of 4.83.
- Executive summary:
The experimental value of octanol water partition co-efficient (log Pow) of 2,2,2-trifluoroacetamide by Shake flask method was found to be 0.72509 at temperature 23 degC and pH of 4.83.This value indicates that 2,2,2-trifluoroacetamide is relatively intermediate in nature.
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