Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 213-313-4 | CAS number: 936-49-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The substance did not show genotoxic effects in two Ames tests with Salmonella typhimurium TA 98, TA 100, TA 1535, TA 1537, and TA 1538 (10 -5000 microgram/plate), in the Chinese Hamster Ovary K1 cells (20 -1000 mg/l), in two V79 Chinese hamster lung cell tests (0 -1800 mg/l), all with and without metabolic activation.
However, the high boiling fraction from the manufacture of 2-phenyl-2 -imidazoline, consisting of the target compound, its N,N-dibenzoyldiamine derivatives, and other impurities did show genotoxic effects in an Ames test -but only without metabolic activation- with Salmonella typhimurium TA 98, TA 100, TA 102, TA 1535, and TA 1537 (50 -5000 microgram/plate), with a cytotoxic concentration of 1600 microgram/plate (TA100 did not show a cytotoxic effect at all).
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
For this substance no classification according to CLP for genetic toxicity is required
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