Registration Dossier
Registration Dossier
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EC number: 205-029-4 | CAS number: 131-56-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Link to relevant study records
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
- Species / strain / cell type:
- S. typhimurium, other: TA98/100/1535/1537/1538
- Metabolic activation:
- with and without
- Metabolic activation system:
- rat S9 fraction
- Test concentrations with justification for top dose:
- 0.1 to 500 microgram/plate
- Vehicle / solvent:
- DMSO
- Species / strain:
- S. typhimurium, other: TA98/100/1535/1537/1538
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
- Conclusions:
- Interpretation of results (migrated information):
negative
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
Justification for classification or non-classification
At the found effect levels there is no requirement for classification
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