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EC number: 219-417-6 | CAS number: 2432-99-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to aquatic algae and cyanobacteria:
- EC50 (72h) = 23 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC10 (72h) = 5.8 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- NOEC (72h) = 4.5 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC50 (72h) = 53 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC10 (72h) = 10 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)
- NOEC (72h) = 4.5 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 53 mg/L
- EC10 or NOEC for freshwater algae:
- 4.5 mg/L
Additional information
In a 72 hour acute toxicity study, the cultures of Pseudokirshneriella subcapitata were exposed to 11 -aminoundecanoic acid at nominal concentrations of 0 / 4.5 / 7.4 / 12.3 / 20.2 / 33.4 / 55.1 / 90.9 / 150 mg/L under static conditions in accordance with the OECD guideline 201.
Based on cell density 72h-NOEC=4.5 mg/L
72h-EC50= 23 mg/L
Based on growth rate 72h-NOEC=4.5 mg/L
72h-EC50 = 53 mg/L
Only a small abnormality was noted (turgid cells at concentrations of 150, 90.9 and 55.1 mg/L) but is not enought to invalidate the test.
As all validity criteria were fulfilled, OECD guideline and GLP requirements were followed and this study can be considered as valid without restriction.
Therefore, according to the Directive 67/548/EC, in the tested conditions 11 aminoundecanoic acid is considered as harmful for algae based on growth rate. However, the susbtance is not classified according to CLP criteria for algae.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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