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Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
genetic toxicity in vitro
Remarks:
Type of genotoxicity: other: QSAR estimate
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: this model was developed for regulatory assessment of chemical substances
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: QSAR estimate
GLP compliance:
no
Remarks:
not applicable to QSAR models
Type of assay:
other: CAESAR QSAR model for Mutagenicity v.1.0.0.5

Test material

Constituent 1
Reference substance name:
SMILES
IUPAC Name:
SMILES

Results and discussion

Any other information on results incl. tables

Overview of QSAR/SAR estimations on mutagenicity potential of chloroethylene

Method

 

Results

Remarks

Reference

CAESAR

QSAR

model for

Mutagenicity

v.1.0.0.5

Activity: Mutagen

(refer Appendix 3 to this CSR)

Supportive data

CAESAR

QSAR model

for Mutagenicity

v.1.0.0.5

Applicant's summary and conclusion

Conclusions:
not mutagenic