Registration Dossier
Registration Dossier
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EC number: 918-973-3 | CAS number: 1174522-45-2
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Short-term studies:
Hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics, has not been evaluated for sediment toxicity, however, the toxicity of hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, has been evaluated with two organisms and these data are used as read-across to hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics.
The two organisms that have been tested include the marine amphipod, Corophium volutator, a sediment reworker, and the marine filter-feeding bivalve Abra alba. Several studies are available for both species, however, only two studies for each organism have been summarized in this dossier. The two studies present the lowest and highest effect loadings among all the studies.
Corophium volutator was exposed to sediment spiked with hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, for 10 days. Fourteen studies were available and provided LL50 values that ranged from 200 to 1220 mg/kg sediment (dw). The geometric mean of LL50 values from the 14 stuides was 519 mg/kg sediment (dw).
The studies with Abra alba were exposed not to spiked sediment, but to a suspension of sediment in seawater that also included microencapsulated test material. The endpoint measured was fecal pellet production. The EL50 valaues from 4 studies ranged from 36 mg/kg to 103 mg/kg sediment (dw) suspension.
Long-term studies:
Data are not available from a long-term sediment toxicity study. The substance is a hydrocarbon UVCB for which standard tests for this endpoint are intended for single substances and are not appropriate for this complex substance. However, this endpoint is characterized for representative hydrocarbon structures that comprise the hydrocarbon blocks used to assess the environmental risk of this substance with the PETRORISK model (see library tab in PETRORISK spreadsheet attached in IUCLID section 13).
Key value for chemical safety assessment
Additional information
Short-term studies:
Hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics, has not been evaluated for sediment toxicity, however, the toxicity of hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, has been evaluated with two organisms and these data are used as read-across to hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics.
The two organisms that have been tested include the marine amphipod, Corophium volutator, a sediment reworker, and the marine filter-feeding bivalve Abra alba. Several studies are available for both species, however, only two studies for each organism have been summarized in this dossier. The two studies present the lowest and highest effect loadings among all the studies.
Corophium volutator was exposed to sediment spiked with hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, for 10 days. Fourteen studies were available and provided LL50 values that ranged from 200 to 1220 mg/kg sediment (dw). The geometric mean of LL50 values from the 14 stuides was 519 mg/kg sediment (dw).
The studies with Abra alba were exposed not to spiked sediment, but to a suspension of sediment in seawater that also included microencapsulated test material. The endpoint measured was fecal pellet production. The EL50 valaues from 4 studies ranged from 36 mg/kg to 103 mg/kg sediment (dw) suspension.
Long-term studies:
Data are not available from a long-term sediment toxicity study. The substance is a hydrocarbon UVCB for which standard tests for this endpoint are intended for single substances and are not appropriate for this complex substance. However, this endpoint is characterized for representative hydrocarbon structures that comprise the hydrocarbon blocks used to assess the environmental risk of this substance with the PETRORISK model (see library tab in PETRORISK spreadsheet attached in IUCLID section 13).
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