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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not known whether GLP or not

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1987

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 202 (1984)
Deviations:
yes
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloro-5-trifluoromethyl-2-pyridylamine
EC Number:
401-670-0
EC Name:
3-chloro-5-trifluoromethyl-2-pyridylamine
Cas Number:
79456-26-1
Molecular formula:
C6H4ClF3N2
IUPAC Name:
3-chloro-5-(trifluoromethyl)pyridin-2-amine

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
semi-static
Total exposure duration:
21 d

Test conditions

Hardness:
250 mg CaCO3/l
pH:
7.4 - 9.6
Dissolved oxygen:
4.5 - 8.9 mg/l
Details on test conditions:
Magnetic stirring during 72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
6.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
1.9 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
6.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: parental mortality
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
12.6 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: parental mortality
Details on results:
First brood after 8 days
20% mortality of parents in control
Large variation in pH and disolved oxygen

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
21-day NOEC: 6.2 mg/l (reproduction Daphnia magna)
Executive summary:

21-day NOEC: 6.2 mg/l (reproduction Daphnia magna)