Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1987
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not known whether GLP or not

Data source

Reference
Reference Type:
other company data
Title:
Unnamed

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloro-5-trifluoromethyl-2-pyridylamine
EC Number:
401-670-0
EC Name:
3-chloro-5-trifluoromethyl-2-pyridylamine
Cas Number:
79456-26-1
Molecular formula:
C6H4ClF3N2
IUPAC Name:
3-chloro-5-(trifluoromethyl)pyridin-2-amine

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
90 days

Results and discussion

Effect levels

Dose descriptor:
NOEL
Effect level:
2 mg/kg bw/day (nominal)

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
90-day NOEL, oral, rat: 2 mg/kg/day
Executive summary:

90-day NOEL, oral, rat: 2 mg/kg/day