Registration Dossier
Registration Dossier
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EC number: 401-670-0 | CAS number: 79456-26-1 ACTF; P-007
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- sub-chronic toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1987
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Not known whether GLP or not
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-chloro-5-trifluoromethyl-2-pyridylamine
- EC Number:
- 401-670-0
- EC Name:
- 3-chloro-5-trifluoromethyl-2-pyridylamine
- Cas Number:
- 79456-26-1
- Molecular formula:
- C6H4ClF3N2
- IUPAC Name:
- 3-chloro-5-(trifluoromethyl)pyridin-2-amine
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
- Duration of treatment / exposure:
- 90 days
Results and discussion
Effect levels
- Dose descriptor:
- NOEL
- Effect level:
- 2 mg/kg bw/day (nominal)
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- 90-day NOEL, oral, rat: 2 mg/kg/day
- Executive summary:
90-day NOEL, oral, rat: 2 mg/kg/day
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