Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1987
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not known whether GLP or not

Data source

Reference
Reference Type:
other company data
Title:
Unnamed

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloro-5-trifluoromethyl-2-pyridylamine
EC Number:
401-670-0
EC Name:
3-chloro-5-trifluoromethyl-2-pyridylamine
Cas Number:
79456-26-1
Molecular formula:
C6H4ClF3N2
IUPAC Name:
3-chloro-5-(trifluoromethyl)pyridin-2-amine

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
90 days

Results and discussion

Effect levels

Dose descriptor:
NOEL
Effect level:
2 mg/kg bw/day (nominal)

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
90-day NOEL, oral, rat: 2 mg/kg/day
Executive summary:

90-day NOEL, oral, rat: 2 mg/kg/day