Registration Dossier
Registration Dossier
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EC number: 253-168-4 | CAS number: 36727-29-4
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
Parent compound 3,5,5-trimethylhexanoyl chloride: No data available.
Hydrolysis product 3,5,5-trimethylhexanoic acid: 96h LC50 > 120 mg/L
(nominal, test item conc. analytically verified), Danio rerio,
OECD 203 (BASF SE, 2018, Study ID 170915BH/FAZ17987).
Based on the available results, the hydrolysis product 3,5,5-trimethylhexanoic acid is acutely not harmful to fish (LC50 > 120 mg/L).
Long-term toxicity to fish:
No data available.
Short-term toxicity to aquatic invertebrates:
Parent compound 3,5,5-trimethylhexanoyl chloride: 48h EC50 = 26.9 mg/L (nominal, test item conc. not analytically verified), Daphnia magna, Directive 79/831/EEC, Annex V, Part C (BASF AG, 1989) .
Hydrolysis product 3,5,5-trimethylhexanoic acid: 48h EC50 = 68 mg/L (nominal, test item conc. analytically verified), Daphnia magna, OECD 202 (Harlan, 2010, C84121).
Based on the available results 3,5,5-trimethylhexanoyl chloride and the hydrolysis product 3,5,5-trimethylhexanoic acid are considered to be acutely harmful to aquatic invertebrates.
Long-term toxicity to aquatic invertebrates:
No data available.
Growth inhibition to aquatic algae:
Parent compound 3,5,5-trimethylhexanoyl chloride: 72h ErC50 = 40.8 mg/L; 72h ErC10 = 26.3 mg/L (neutralised: 72h ErC50= 311.7 mg/L; 72h ErC10 = 108.1 mg/L) (nominal, test item conc. not analytically verified), Desmodesmus subspicatus, DIN 38412, Part 9 (BASF AG, 1990).
Hydrolysis product 3,5,5-trimethylhexanoic acid: 72h ErC50 = 81 mg/L;
72h ErC10 = 45 mg/L (nominal, test item conc. analytically verified), Pseudokirchneriella
subcapitata, OECD 201 (Harlan, 2010/C84132).
Based on the available results, 3,5,5-trimethylhexanoyl chloride is considered to be acutely harmful to aquatic algae. With high probability the substance is acutely not harmful to aquatic algae after neutralisation.
The hydrolysis product 3,5,5-trimethylhexanoic acid is considered to be acutely harmful to aquatic algae.
Toxicity to microorganisms:
Parent compound 3,5,5-trimethylhexanoyl chloride: 3h EC50 = 450 mg/L, EG-Guideline 88/302/EGW (BASF AG, 1990).
Hydrolysis product 3,5,5-trimethylhexanoic acid: 3h EC50 = 470 mg/L, 3h
EC10/NOEC = 230 mg/L, OECD 209 (Oxea, 1989).
The inhibition of the degradation activity of activated slugde is not anticipated when indroduced in appropriate low concentrations.
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