Registration Dossier
Registration Dossier
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EC number: 253-256-2 | CAS number: 36888-99-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- Parameter ranges: In domain; Structural domain: Out of domain (Correct fragments: 90.91%; Incorrect fragments: 0%; Unknown fragments: 9.09%); Unable to mineralize: In domain
- Principles of method if other than guideline:
- Estimation of results of OECD screening tests on ready biodegradation in water: CATALOGIC (v5.14.1.5); CATALOGIC 301C v.11.16
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Parameter:
- half-life in days (QSAR/QSPR)
- Remarks on result:
- other: Primary half life: < 1 day; Ultimate half life: 2m 28d
- Details on results:
- Model domain similarity:
- Parametric domain: 100%
- Structural domain: 90.91% (correct fragments), 0% (incorrect fragments), 9.09% (unknown fragments)
- Mechanistic domain: 100%
Predicted BOD value: 0.20 +/- 6.92 E-3
Prediction: Not ready degradable - Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test substance is not readily biodegradable (according to OECD criteria)
- Endpoint:
- biodegradation in water: ready biodegradability
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- See attached justification
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
Referenceopen allclose all
Description of key information
Poorly biodegradable.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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