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Partition coefficient

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Description of key information

Log Kow not used to predict the bioaccumulation potential of Quaternary ammonium compounds, di-C16-18 (even numbered)-alkyldimethyl, chlorides.

Key value for chemical safety assessment

Log Kow (Log Pow):
10
at the temperature of:
25 °C

Additional information

A partition coefficient 1-octanol/water test for quaternary ammonium compounds benzyl bis (hydrogenated tallow-alkyl) methyl chlorides (trade name Noramium MB2HT) has been performed according to OECD guideline for testing of chemicals, No. 123. In the test conditions, Log Pow determined is above 10. The slow-stirring method is considered to be the best to determine the Kow of surfactants, as indicated in the Chapter R.7A of the REACH guidance (Section R.7.1.8.3; Guidance on regulatory compliant Kow determination for surfactants). However, it is also indicated that this method is still not demonstrated to be perfect and that none of the experimental methods is very well suited for determining the Kow of surface active chemicals. Indeed, due to the physico-chemical properties of surfactants, specifically their tendency to either accumulate at the octanol/water interface or to coat the surfaces of the above-described HPLC adsorbent phase, the logKow of surfactants cannot be accurately measured for these substances. Therefore, the available experimentally determined and higher tier sorption and BCF/BAF figures are used to predict the fate in the environment.

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