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EC number: 233-226-5 | CAS number: 10094-45-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the analogue justification attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Parameter:
- % degradation (O2 consumption)
- Value:
- 8
- Sampling time:
- 28 d
- Remarks on result:
- other: Balk, 1989, Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 23
- Sampling time:
- 28 d
- Remarks on result:
- other: Balk, 1989, RDA
- Parameter:
- % degradation (O2 consumption)
- Value:
- < 10
- Sampling time:
- 28 d
- Remarks on result:
- other: van Ginkel 1988;Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 16
- Sampling time:
- 28 d
- Remarks on result:
- other: 0.15% SSA dipersion
- Remarks:
- Kolvenbach 1989; Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 20
- Sampling time:
- 28 d
- Remarks on result:
- other: 0.020% SSA dispersion
- Remarks:
- Kolvenbach 1989, Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 24
- Sampling time:
- 28 d
- Remarks on result:
- other: Maximum degree of degradation with non-adapted inoculum
- Remarks:
- Kolvenbach 1989, Sturm test
- Parameter:
- % degradation (O2 consumption)
- Value:
- 19
- Sampling time:
- 28 d
- Remarks on result:
- other: Maximum degree of degradation with non-adapted inoculum
- Remarks:
- Kolvenbach 1989, Sturm test
- Conclusions:
- Not readily biodegradable: < 10% - 24% degradation (OECD 301 D, 301 F, DGXI/400/84 EEC 19984, L251, 1984.09.19, Part C, EEC 1984)
- Executive summary:
Studies on the ready biodegradability of (Z)-N-octadecyldocos-13-enamide (CAS No. 10094-45-8) are not available. Therefore data of the analogue substance N-octadecylstearamide (stearyl stearamide, CAS 13276 -08 -9) were used as read-across. The ready biodegradability of N-octadecylstearamide (stearyl stearamide, CAS 13276 -08 -9) was investigated in five tests.
The first study comprises a test according to OECD guideline 301 D and a repetitive die away test following DGXI/400/84, EEC 1984 (Balk, 1989). Both tests were carried out under GLP and have a test duration of 6 weeks. In the OECD closed bottle test 2.04 mg/L of the substance was incubated with domestic activated sludge. The substance reached 8% degradation after 28 days and 9% degradation after 42 days. In the die away test 40 mg/L of the substance was incubated with industrial non-adapted activated sludge as inoculum. Degradation rates were 23% after 28 days and 29% after 42 days. The second study is a closed bottle test equivalent to the guideline L251, 1984.09.19, Part C, EEC 1984 (van Ginkel, 1988). Domestic activated sludge was used as inoculum and incubated with 2 mg/L of the substance. The degradation after 28 days was < 10%. The third study comprises two tests according to OECD guidelines 301 D and 301 F (Kolvenbach, 1989) using effluent from a municipal waste water treatment plant as inoculum. The closed bottle test applying 1.8 ppm of the substance resulted in 20% degradation after 28 days. The CO2 evolution test applying 10 and 20 ppm of the substance resulted in maximum degradation rates of 24% with non-adapted inoculum and 19% with adapted inoculum. Altogether it is stated that the substance can be regarded as not readily biodegradable under OECD criteria.
Reference
Description of key information
Not readily biodegradable: < 10% - 24% degradation (OECD 301 D, 301 F, DGXI/400/84 EEC 19984, L251, 1984.09.19, Part C, EEC 1984)
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Studies on the ready biodegradability of (Z)-N-octadecyldocos-13-enamide (CAS No. 10094-45-8) are not available. Therefore data of the analogue substanceN-octadecylstearamide (stearyl stearamide, CAS 13276-08-9) were used as read-across.The read-across is justified due to the structural similarity of the analogue substances and similar physico-chemical properties resulting in a similar environmental fate and ecotoxicity profile.This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 6.1) and within the category justification attached in IUCLID Section 13. The ready biodegradability of N-octadecylstearamide (stearyl stearamide, CAS 13276-08-9) was investigated in five tests.
The first study comprises a test according to OECD guideline 301 D and a repetitive die away test following DGXI/400/84, EEC 1984 (Balk, 1989). Both tests were carried out under GLP and have a test duration of 6 weeks. In the OECD closed bottle test 2.04 mg/L of the substance was incubated with domestic activated sludge. The substance reached 8% degradation after 28 days and 9% degradation after 42 days. In the die away test 40 mg/L of the substance was incubated with industrial non-adapted activated sludge as inoculum. Degradation rates were 23% after 28 days and 29% after 42 days. The second study is a closed bottle test equivalent to the guideline L251, 1984.09.19, Part C, EEC 1984 (van Ginkel, 1988). Domestic activated sludge was used as inoculum and incubated with 2 mg/L of the substance. The degradation after 28 days was < 10%. The third study comprises two tests according to OECD guidelines 301 D and 301 F (Kolvenbach, 1989) using effluent from a municipal waste water treatment plant as inoculum. The closed bottle test applying 1.8 ppm of the substance resulted in 20% degradation after 28 days. The CO2 evolution test applying 10 and 20 ppm of the substance resulted in maximum degradation rates of 24% with non-adapted inoculum and 19% with adapted inoculum. Altogether it is stated that the substance can be regarded as not readily biodegradable under OECD criteria.
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