Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Endpoint:
cytotoxicity
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Toxicity of ethanol, n-butanol & iso-amyl alcohol in saccharomyces cerevisiae when supplied separately and in mixtures
Author:
Okolo B et al.
Year:
1981
Bibliographic source:
Biotechnology Letters 9, 431-434
Reference Type:
secondary source
Title:
No information
Author:
RIFM
Year:
2009
Bibliographic source:
RIFM database

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
no
Type of method:
in vitro
Endpoint addressed:
not applicable

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methylbutan-1-ol
EC Number:
204-633-5
EC Name:
3-methylbutan-1-ol
Cas Number:
123-51-3
Molecular formula:
C5H12O
IUPAC Name:
3-methylbutan-1-ol
Details on test material:
- Name of test material (as cited in study report): Iso-amyl alcohol

Test animals

Species:
other: Saccharomyces cerevisiae D
Strain:
not specified

Administration / exposure

Route of administration:
other: in medium
Vehicle:
unchanged (no vehicle)
Analytical verification of doses or concentrations:
no
Duration of treatment / exposure:
12 h
Frequency of treatment:
single application
Post exposure period:
no data
No. of animals per sex per dose:
not applicable

Results and discussion

Details on results:
LD20 = 1900 mg/kg
LD50 = 4300 mg/kg

Applicant's summary and conclusion