3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium, 4-hydroxy-N,N,N,10-tetramethyl-9-oxo-, inner salt, 4-oxide

Oxidising properties

Administrative data

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 November 2008 to 19 March 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

This study was conducted in accordance with the relevant international Guideline (EC Test A.17). The study report presented the relevant information to confirm the validity of the study and the methodology presented is sufficient to make the study wholly reproduceable.

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Deviations:

no

Principles of method if other than guideline:

N/A

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP Regulation (1999)

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

417-560-0

EC Name:

-

Cas Number:

67881-98-5

Molecular formula:

C11H22NO6P

IUPAC Name:

trimethyl[2-({2-[(2-methylprop-2-enoyl)oxy]ethyl phosphonato}oxy)ethyl]azanium

Details on test material:

- Name of test material (as cited in study report): HEMA-PC (2-Methacryloyloxyethyl-2'-(trimethylammoniumethyl) phosphate
- Substance type: Pure Active Substance
- Physical state: Solid
- Analytical purity: 99 % (98-101 %)
- Impurities (identity and concentrations): 0.1 % by area (HPLC)
- Purity test date: 29 September 2008
- Lot/batch No.: SS148076
- Expiration date of the lot/batch: 27 October 2009 (lab default)
- Stability under test conditions: Stable
- Storage condition of test material: Under nitrogen at -20 degrees celsius in the dark.
- Other: N/A

Study design

Contact with:

powdered cellulose

Results and discussion

Test results (Oxidising solids)

Test results (Oxidising solids) 1

Sample tested:

test mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Remarks on result:

other: result not specified (migrated information)

Remarks:

No burning rates of the test item could be recorded under the conditions of the test due to self-extinguishing

Test results (Oxidising solids) 2

Sample tested:

reference mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

93 s

Remarks on result:

other: 60 % Barium Nitrate/Cellulose

Test results (Oxidising solids) 3

Sample tested:

reference mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

119 s

Remarks on result:

other: 100 % Cellulose

Any other information on results incl. tables

N/A

Applicant's summary and conclusion

Interpretation of results:

other: no oxidising properties

Remarks:

Migrated information

Conclusions:

Testing for oxidising properties of HEMA-PC was conducted successfully for HEMA-PC. HEMA-PC is not considered an oxidising substance.

Executive summary:

Testing for oxidising properties of HEMA-PC was conducted successfully for HEMA-PC in accordance with EC Test A.17.. HEMA-PC is not considered an oxidising substance.