Registration Dossier
Registration Dossier
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EC number: 201-807-2 | CAS number: 88-18-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Microorganisms were exposed to the analogue, o-sec-butylphenol, where the 3 hr EC50 was > 10 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 mg/L
Additional information
There are no reliable toxicity studies available for toxicity of o-tert-butylphenol to activated sludge microorganisms. However, reliable data are available for the analogue, o-sec-butylphenol and are included in the dossier.
Horton et al. (1991) conducted a reliable study on the toxicity of the analogue, o-sec-butylphenol, to activated sludge microorganisms following OECD 209 guidelines. Activated sludge microorganisms were exposed to the a control and 10 mg/L of the test substance for 3 hrs. Oxygen consumption was measured to determine the 3 hr EC50 of > 10 mg/L. Consequently, this value is taken to fullfil the toxicity to microorganisms endpoint.
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