Registration Dossier
Registration Dossier
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EC number: 921-577-3 | CAS number: 1174918-60-5
Endpoint summary
Administrative data
Description of key information
Additional information
The hydrocarbon block method has been used for environmental risk assessment (see REACH guidance, R7, app.13-1). Aquatic PNECs for hydrocarbon blocks have been derived using the HC5 statistical extrapolation method and the target lipid model using representative structures. See Product Library tab in PETRORISK spreadsheet attached to IUCLID Section 13. Given the large database of freshwater organisms included in the target lipid model, an assessment factor of one has been applied to the HC5.Acute toxicity data was available for n-pentane for fish, invertebrates and algae and an acute toxicity study was available for 2-methylbutane usingDaphnia magna. The lowest acute LC50or EC50value was for 2-methylbutane usingDaphnia magnawith an EC50of 2.3 mg. l-1A similar EC50of 2.7 was also reported for n-pentane.The results indicates that the pentane substances would not meet the criteria for toxic in the PBT assessment. However, the 48 hr EC50of 2.3 mg/l reported forDaphnia magnawould result in a GHS classification of acute category 2 with the hazard phrase ' toxic to aquatic life'.
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