Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 308-760-8 | CAS number: 98246-87-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The BCF for the substance is calculated to be 3.968 L/kg ww
Additional information
At log Kow values between 4 and 5, log BCF increases linearly with log Kow. This linear relationship is the basis for the B screening criterion of log Kow > 4.5. At very high log Kow (>6), a decreasing relationship between the two parameters is observed, so even if the high log Kow value of AKD initially indicates a high bioaccumulation potential, there are reports pointing out that the likeliness of bioaccumulation declines with log Kow values above 6, and the aquatic BCF of a substance is probably lower than 2000 l/kg if the calculated log Kow is higher than 10 (TGD R.11, p. 28). The very high log Kow value (14.2) therefore suggests that AKD should be considered as not bioaccumulating.
Additionally direct and indirect exposure of the aquatic compartment is limited, the bioavailability of the substance is very low, and no specific uptake mechanism apart from lipophilic partitioning is known or suspected.
In conclusion, AKD does not fulfil the bioaccumulation criteria and should not be considered as bioaccumulating (B) or very bioaccumulating (vB).
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