Registration Dossier
Registration Dossier
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EC number: 619-079-3 | CAS number: 949109-75-5
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Partition coefficient: >9 for all constituents of the substance (OECD 117)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 9
Additional information
A measured log Kow value of >9.4 was obtained for all constituents of the substance using HPLC method in accordance with OECD 117 and in compliance with GLP. The result is considered to be reliable. An overall limit log Kow value of 9 will be used for assessment purposes; this is because log Kow above 9 is not scientifically meaningful.
This is supported by a reliable evaluation using QSAR. For UVCB substances, it is useful to consider the properties of constituents of the substance, which can be very important in the chemical safety assessment. In the case of Plant sterols, the SRC KOWWIN method has been used to estimate the log Kow values of seven constituents of Plant sterols individually. These constituents together comprise 99% w/w of the registration substance (based on average composition). For all of these substances, log Kow values greater than or equal to 8.0 are estimated using this method. In this range, the chemcial safety assessment is not sensitive to the exact value of log Kow. This finding is therefore considered to be reliable supporting data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
