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Toxicological information

Repeated dose toxicity: inhalation

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Administrative data

Endpoint:
sub-chronic toxicity: inhalation
Type of information:
experimental study planned (based on read-across)
Justification for type of information:
A sub-chronic toxicity study (90-day), inhalation route (test method OCED 413) will be commissioned as per ECHA compliance check decision CCH-D-2114394043-52-01/F.

See rationale and justification for the analogue read-across approach for the registration of the nanoform of Pigment Red 002 (chapter 13).
Cross-reference
Reason / purpose for cross-reference:
read-across source
Reference
Endpoint:
sub-chronic toxicity: inhalation
Data waiving:
other justification
Justification for data waiving:
other:
Critical effects observed:
not specified

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 413 (90-Day (Subchronic) Inhalation Toxicity Study

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[(2,5-dichlorophenyl)azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide
EC Number:
227-930-1
EC Name:
4-[(2,5-dichlorophenyl)azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide
Cas Number:
6041-94-7
Molecular formula:
C23H15Cl2N3O2
IUPAC Name:
4-[(2,5-dichlorophenyl)diazenyl]-3-hydroxy-N-phenyl-2-naphthamide
Test material form:
solid: nanoform, no surface treatment

Test animals

Species:
rat

Results and discussion

Applicant's summary and conclusion

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