Registration Dossier
Registration Dossier
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EC number: 212-485-8 | CAS number: 822-06-0
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.049 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.005 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 8.42 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.674 mg/kg sediment dw
- Assessment factor:
- 100
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.067 mg/kg sediment dw
- Assessment factor:
- 1 000
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.523 mg/kg soil dw
- Assessment factor:
- 100
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Classification and labelling according to aquatic toxicity data
Justification for classification or non classification
Three acute tests have been performed with fish, daphnia and algae. No effects have been observed up to the highest concentrations tested (algae: 77 mg/l, fish: 83 mg/l, daphnia: 90 mg/l). Therefore, a classification related to risk phrases R50, 51, 52 can be ruled out.
Classification and labelling according to degradation and bioconcentration
Justification for classification or non classification
Hexamethylene diisocyanate is not readily biodegradable and has a logPow of 3.2 (calculated). However, the substance hydrolysis rapidly within 1 hour. The hydrolysis product is - beside insoluble oligomeric and polymeric ureas - the corresponding Hexamethylenediamine. The latter has a logPow of 0.02 (measured). Therefore, a classification related to risk phrase R53 is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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