Registration Dossier
Registration Dossier
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EC number: 200-662-2 | CAS number: 67-64-1
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Justification for classification or non-classification
No classification based on available data from dermal carcinogenicity studies supported by absence of a genotoxic activity.
Additional information
There are no studies available with long-term exposure to acetone via oral uptake or inhalation.
Acetone has been used as vehicle or solvent in a multitude of dermal carcinogenicity studies with up to life-time application to several strains of mice. As the acetone treated groups represented the vehicle control group, no additional negative control groups were investigated except in a single study. In summary, there are no indications of an elevated tumor incidence in acetone-treated vehicle control groups demonstrating a lack of a carcinogenic potential of acetone itself.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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