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Administrative data

Description of key information

The substance is known to be corrosive to skin so acute toxicity testing is unjustified. The substance is an intermediate used under SCC and therefore exposure via oral, dermal and /or inhalation is unlikely.

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited publication.
Principles of method if other than guideline:
no information
Species:
rat
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 600 mg/kg bw
Interpretation of results:
study cannot be used for classification
Conclusions:
LD50 2600 mg/kg bw. Outcome comparable to that of glycolic acid.
Executive summary:

LD50 2600 mg/kg bw. Outcome comparable to that of glycolic acid.

Endpoint conclusion
Endpoint conclusion:
no study available
Quality of whole database:
No valid data available. K4: Limited publication.

Acute toxicity: via inhalation route

Link to relevant study records
Reference
Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited publication.
Principles of method if other than guideline:
no information
Species:
rat
Interpretation of results:
study cannot be used for classification
Conclusions:
Inhalation of air saturated with vapor for 4 hours does not result in deaths. Outcome comparable to that of benzyl alcohol.
Executive summary:

Inhalation of air saturated with vapor for 4 hours does not result in deaths. Outcome comparable to that of benzyl alcohol.

Endpoint conclusion
Endpoint conclusion:
no study available
Quality of whole database:
No valid data available. K4: Limited publication.

Acute toxicity: via dermal route

Link to relevant study records
Reference
Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited publication.
Principles of method if other than guideline:
no information
Species:
guinea pig
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 mL/kg bw
Interpretation of results:
study cannot be used for classification
Conclusions:
LD50 1ml/kg bw (rel. density = 1.25 ~ 1250 mg/kg bw)
Executive summary:

LD50 1ml/kg bw (rel. density = 1.25 ~ 1250 mg/kg bw)

Endpoint conclusion
Endpoint conclusion:
no study available
Quality of whole database:
No valid data available. K4: Limited publication.

Additional information

Justification for classification or non-classification

The substance is corrosive to skin so acute toxicity testing is unjustified. The substance is an intermediate used under SCC and therefore exposure via oral, dermal and /or inhalation is unlikely. Based on this information no C&L is proposed.