Registration Dossier
Registration Dossier
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EC number: 201-942-7 | CAS number: 89-81-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1975
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Abstract only.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- 6-isopropyl-3-methylcyclohex-2-enone
- EC Number:
- 201-942-7
- EC Name:
- 6-isopropyl-3-methylcyclohex-2-enone
- Cas Number:
- 89-81-6
- Molecular formula:
- C10H16O
- IUPAC Name:
- 6-isopropyl-3-methylcyclohex-2-enone
- Test material form:
- gas under pressure: refrigerated liquefied gas
- Details on test material:
- Name: Piperitone
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No Data
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Details on dermal exposure:
- The test substance was administered dermally to rabbits at a range of concentrations and the rabbits were observed for fourteen days.
- Duration of exposure:
- No data
- Doses:
- 2.5 g/kg and 5 g/kg.
- No. of animals per sex per dose:
- Four rabbits at 2.5 g/kg and Six rabbits at 5 g/kg.
- Control animals:
- no
- Details on study design:
- The test substance was administered dermally to rabbits at a range of concentrations and the rabbits were observed for fourteen days.
Results and discussion
- Mortality:
- Two rabbits dies on day 2 at 5 g/kg.
Any other information on results incl. tables
| Dose g/kg | Deaths/No. Animals | D1 | D2 | D3 | D4 | D5 | D6 | D7 | D8 | D9 | D10 | D11 | D12 | D13 | D14 |
| 2.5 | 0/4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5.0 | 2/6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: other:
- Conclusions:
- The test substance was administered dermally to rabbits at a range of concentrations and the rabbits were observed for fourteen days.
- Executive summary:
The test substance was administered dermally to rabbits at a range of concentrations and the rabbits were observed for fourteen days.
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