Registration Dossier
Registration Dossier
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EC number: 205-753-0 | CAS number: 150-13-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- European Commission
- Year:
- 2 006
- Bibliographic source:
- SCCP/1008/06
Materials and methods
Test guideline
- Guideline:
- other: no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-aminobenzoic acid
- EC Number:
- 205-753-0
- EC Name:
- 4-aminobenzoic acid
- Cas Number:
- 150-13-0
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 4-aminobenzoic acid
Constituent 1
Test animals
- Species:
- human
Test system
- Type of coverage:
- occlusive
- Vehicle:
- other: a sunscreen formulation
- Controls:
- yes
- Amount / concentration applied:
- 5% in vehicle
- Duration of treatment / exposure:
- 48 h
- Observation period:
- 96 h
- Number of animals:
- 50
Results and discussion
In vivo
Results
- Irritation parameter:
- other: see SCCP report
- Basis:
- mean
- Time point:
- other: 96 h
- Score:
- 0
- Max. score:
- 70
- Remarks on result:
- other: 5% solution of the substance in a sunscreen formulation
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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