Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 205-753-0 | CAS number: 150-13-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- European Commission
- Year:
- 2 006
- Bibliographic source:
- SCCP/1008/06
Materials and methods
Test guideline
- Guideline:
- other: no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-aminobenzoic acid
- EC Number:
- 205-753-0
- EC Name:
- 4-aminobenzoic acid
- Cas Number:
- 150-13-0
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 4-aminobenzoic acid
Constituent 1
Test animals
- Species:
- human
Test system
- Type of coverage:
- occlusive
- Vehicle:
- other: a sunscreen formulation
- Controls:
- yes
- Amount / concentration applied:
- 5% in vehicle
- Duration of treatment / exposure:
- 48 h
- Observation period:
- 96 h
- Number of animals:
- 50
Results and discussion
In vivo
Results
- Irritation parameter:
- other: see SCCP report
- Basis:
- mean
- Time point:
- other: 96 h
- Score:
- 0
- Max. score:
- 70
- Remarks on result:
- other: 5% solution of the substance in a sunscreen formulation
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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