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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
one-generation reproductive toxicity
Remarks:
based on test type (migrated information)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
European Commission
Year:
2006
Bibliographic source:
SCCP/1008/06

Materials and methods

Test guideline
Guideline:
OECD Guideline 415 [One-Generation Reproduction Toxicity Study (before 9 October 2017)]
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-aminobenzoic acid
EC Number:
205-753-0
EC Name:
4-aminobenzoic acid
Cas Number:
150-13-0
Molecular formula:
C7H7NO2
IUPAC Name:
4-aminobenzoic acid

Test animals

Species:
rat
Strain:
Long-Evans
Sex:
male/female

Administration / exposure

Route of administration:
oral: feed
Doses / concentrations
Remarks:
Doses / Concentrations:
1 and 2%
Basis:
nominal in diet
No. of animals per sex per dose:
6

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
NOEC
Effect level:
> 2 other: %
Based on:
test mat.
Sex:
female

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion