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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data from the EU Risk Assessment Report for TCPP

Data source

Reference
Reference Type:
publication
Title:
EU RAR (2008) European Union Risk Assessment Report TRIS(2-CHLORO-1-METHYLETHYL) PHOSPHATE (TCPP) CAS No: 13674-84-5, EINECS No: 237-158-7
Author:
EC
Year:
2008
Bibliographic source:
European Communities, May 2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: no ata
GLP compliance:
not specified
Test type:
other: scientific review

Test material

Constituent 1
Chemical structure
Reference substance name:
Tris(2-chloro-1-methylethyl) phosphate
EC Number:
237-158-7
EC Name:
Tris(2-chloro-1-methylethyl) phosphate
Cas Number:
13674-84-5
Molecular formula:
C9H18Cl3O4P
IUPAC Name:
tris(2-chloro-1-methylethyl) phosphate

Test animals

Species:
rat

Results and discussion

Any other information on results incl. tables

LD50 Rat oral =930 - 1550 mg/kg

Applicant's summary and conclusion

Conclusions:
In accordance with the CLP Regulation criteria, a substance is classified as to its acute oral toxicity if LD50 ≤2 000 mg/kg bw. The acute oral toxicity data here corresponds to Class 4 Acute oral toxicity (300 < LD50 ≤ 2000 mg/kg bw).