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Administrative data

Link to relevant study record(s)

basic toxicokinetics, other
Type of information:
other: assessment

Description of key information

No toxicokinetics studies are available for absorption of assessed substance. Based on its physico-chemcial properties, and available toxicological studies together with QSAR, assessed substance is estimated to be absorbed following oral administration with default value of 100%. Absorption via the dermal route is considered to be relevant with 100% for worst cases and inhalation absorption is estimated with low possibility via exposure to dust or vapor.  


No experimental data on the distribution properties/metabolism/ excretion of assessed substance is available. Accumulation in fat tissue is expected to occur due to lipophilic substance (log P >0). QSAR Database indicated partitioning between the two tissues (brain/blood) at equilibrium is low. And QSAR Database also predicted no metabolism of assessed substance by CYP2C9 and CYP2D6 that are the main cytochromes involved in Humans xenobiotics metabolism.


The assessed substance is considered to be excreted in the urine due to water-soluble and low molecular weight.

Key value for chemical safety assessment

Additional information