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Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics, other
Type of information:
other: Summary in SIDS INITIAL ASSESSMENT PROFILE of Tetraisobutyltitanat
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
SIDS INITIAL ASSESSMENT PROFILE Titanium dioxide CAS 13463-67-7
Author:
OECD
Year:
2013

Materials and methods

Test material

Constituent 1
Reference substance name:
Reference substance 001
Test material form:
solid: nanoform

Results and discussion

Applicant's summary and conclusion

Conclusions:
Feces was the main excretion route of Titanium dioxide. Urinary excretion and whole blood concentrations of titanium were below the limit of quantification (LOQ) after 72 h and concentrations of titanium in liver, kidneys and muscle could not be detected for all tested groups in this oral toxicokinetic study.