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Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 March 2012- 11 July 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been performed according to the EC an UN guidelines and according to the Principles of GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Version / remarks:
(2008)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: UN no. ST/SG/AC.10/11/Rev.5: Part III: Classification Procedures, Test Methods and Criteria Relating to Class 2, Class 3, Class 4, Division 5.1, Class 8 and Class 9, Test N.1: “Test Method for Readily Combustible Solids” (2009)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,5-anhydro-4-{[4-(4-{4-[({1-[(2S,3S)- 2-(benzyloxy)pentan-3-yl]hydrazino}carbonyl)amino]phenyl}piperazin1-yl)phenoxy]methyl}-1,3,4-trideoxy-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-
EC Number:
701-059-1
Cas Number:
345217-03-0
Molecular formula:
C43H50F2N8O4
IUPAC Name:
2,5-anhydro-4-{[4-(4-{4-[({1-[(2S,3S)- 2-(benzyloxy)pentan-3-yl]hydrazino}carbonyl)amino]phenyl}piperazin1-yl)phenoxy]methyl}-1,3,4-trideoxy-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): PAZ-D
- Physical state: white powder
- Hygroscopic

Results and discussion

Any other information on results incl. tables

In contact with the flame of the gas burner the test material melted and turned into a light brown residue. After removal of the ignition source, no propagation of combustion was observed.

Applicant's summary and conclusion

Interpretation of results:
non flammable
Remarks:
Migrated information
Conclusions:
PAZ-D is not highly flammable by ignition. The test was performed in accordance with EC A.10 and UN test N.1 and according to the principles of GLP.
According to CLP Regulation (EC) No. 1272/2008 including its amendments, the substance does not have to be classified for flammability.