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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Neurotoxicity

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Administrative data

Description of key information

No study on the substance is available. However, information on the main constituent CaF2 is available. Fluoride exposure caused sex and dose specific behavioural disruption. No classification is proposed for neurotoxicity according to the CLP Regulation 1272/2008/EC) as the effects observed in the available study are not considered to be indicative of functional impairment, nor is it possible to confirm at which actual received fluoride dose level the observed effects occur.


Therefore, the reaction mass of calcium fluoride and calcium sulfate and calcium carbonate is not considered to be a neurotoxic.

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification