Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 910-697-1 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
No data for toxicity to reproduction are available with the substance identified as reaction mass of calcium fluoride (ca 47.5% w/w), calcium sulfate (ca 22.3% w/w) and calcium carbonate (ca 12.09% w/w). However, fertility studies are available on sodium fluoride as analogue of calcium fluoride, calcium sulfate or calcium carbonate.
Based on a weight of evidence approach using the information on its constituents, no classification of the registered substance is warranted for the toxicty to reproduction according to the criteria of CLP.
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Study duration:
- subacute
- Species:
- rat
Effects on developmental toxicity
Description of key information
No data for developmental toxicity/teratogenicity are available with the substance identified as reaction mass of calcium fluoride (ca 47.5% w/w), calcium sulfate (ca 22.3% w/w) and calcium carbonate (ca 12.09% w/w). However, developmental studies are available on sodium fluoride (as surrogate of calcium fluoride), calcium sulfate or calcium carbonate as described below. Based on a weight of evidence approach using the information on its constituents, no classification of the registered substance is warranted for the developmental toxicty according to the criteria of CLP.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Study duration:
- subchronic
- Species:
- rat
Toxicity to reproduction: other studies
Description of key information
No data
Justification for classification or non-classification
Harmonised classification
Reaction mass of calcium fluoride and calcium sulfate and calcium carbonate has no harmonised classification according to the Regulation (EC) No. 1272/2008 (CLP).
Self classification
Based on the available studies performed on its three main constituents, no additional classification is proposed regarding the toxicity to reproduction (fertility and development) of the reaction mass of calcium fluoride and calcium sulfate and calcium carbonate according to the Annex VI of the Regulation (EC) No. 1272/2008 (CLP).
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
